Decoding the future of

transformative medicines

Our efforts are endless to unlock a world of life-changing
transformative medicines by utilizing Artificial Intelligence

EvolverAI® 2.0– Accelerating
Innovation, Transforming Lives

At BioXcel, we believe there is nothing more important than helping people live healthier, longer lives. Our proprietary AI platform, EvolverAI® 2.0, is the engine behind that mission—harnessing the power of artificial intelligence and human expertise to transform how new medicines are discovered, developed, and delivered.

Molecule to Medicine illustration

Turning Potential Into Proof: From Molecule to Medicine

Our platform’s potential was realized with the discovery and development of IGALMI™ (dexmedetomidine)— a sublingual film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder in adults.

Using EvolverAI and BioXcel, Therapeutics identified and advanced this first-in-class asset from concept to FDA approval in just four years.

This success showcases the unique strength of pairing scientific acumen with AI-driven discovery— addressing unmet clinical needs with unprecedented speed.

EvolverAI Platform Data Foundation

EvolverAI is built on an extensive and diverse dataset, including:

>2B
Relations
>40M
Literature
>1B
Sentences
1M
Ontology
>536K
Clinical Trials
>400K
Intervention Data
~20K
Genes
>40K
Drugs
~9K
Rare Diseases
>100
Major Diseases
15
Therapeutic Areas (TAs)
>100
Proprietary AI Models

Inside the Engine: What Powers EvolverAI® 2.0

EvolverAI® 2.0 is built at the intersection of advanced machine learning and biomedical expertise. What makes this platform powerful is not just its algorithms—but the rich, multi-modal data and real-world knowledge that fuels them.

Key Features
  • Metadata Generation: Uses NLP and relationship mapping to extract deep contextual insights from scientific literature, clinical data, and more
  • Knowledge Graph Creation: Synthesizes structured and unstructured data to build dynamic, interpretable knowledge graphs
  • 100+ Proprietary AI Models: These models reason across diverse datasets—clinical, genomic, phenotypic, and pharmacological—to uncover hidden therapeutic connections
  • Expert-Guided Intelligence: All models are trained and validated by a multidisciplinary team of scientists and clinicians with vast drug discovery experience
EvolverAI 2.0 Engine

AI-Driven Insights

EvolverAI 2.0 supports a wide range of strategic and operational decision-making areas, including:

Opportunity Assessment
Opportunity Assessment

Identify top diseases, compounds, and companies for strategic focus

Licensing & Due Diligence
Licensing & Due Diligence

Accelerate partner evaluation and risk mitigation

Organizational Benchmarking
Organizational Benchmarking

Evaluate and compare external R&D portfolios

Pipeline & Therapy Area Assessments
Pipeline & Therapy Area Assessments

Guide resource allocation with data-driven clarity

Investment Thesis & Recommendations
Investment Thesis & Recommendations

Guide portfolio and pipeline decisions with confidence

Therapeutic Franchise Strategy
Therapeutic Franchise Strategy

Develop focused, scalable therapeutic verticals

Indication/Target/Asset Prioritization
Indication/Target/Asset Prioritization

Streamline selection of high-potential programs

Drug Re-Innovation
Drug Re-Innovation

Repurpose or reposition underutilized assets

Commercial Attractiveness
Commercial Attractiveness

Analyze ROI potential and market dynamics

More Efficient Drug Development

EvolverAI® 2.0 reduces the time, cost, and risk associated with traditional drug development by:

  • Shortening discovery timelines
  • Lowering attrition by prioritizing high-probability candidates
  • Reducing R&D costs via targeted, data-informed decision-making
  • Building robust, de-risked pipelines with therapeutic precision

Whether discovering new molecular entities or reimagining existing compounds, EvolverAI is unlocking therapeutic possibilities at scale.

Efficient Drug Discovery

Built for Breakthroughs

EvolverAI® 2.0 is more than a platform—it’s a launchpad for innovation. By integrating AI with scientific expertise, we are charting a faster, smarter course for life-saving drug discovery.

We are only steps away from the next wave of transformative therapies—and EvolverAI is leading the way.

AI Innovation Launchpad

Let’s Collaborate

We partner with BioPharma companies worldwide to unlock the full potential of their R&D pipelines—enhancing discovery, accelerating timelines, and reducing risk.

Schedule a call with us to learn how EvolverAI® 2.0 can help your team uncover new opportunities, reimagine existing assets, and transform your development strategy.

Schedule a Call Contact Us

Ready to Transform Your R&D Strategy?

Contact us today to explore a discovery call.

Let's Connect

Contact US

info@bioxcel.com
+1 475 237 9007